Prostaglandin D2 serinol amide

A stable analog of PGD2 2-glyceryl ester

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库存: 现货

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1mg

￥1362.00

1090.00

- +
5mg

￥6087.00

4870.00

- +
10mg

￥10837.00

8670.00

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货号: ajci73660
CAS: 851761-42-7
别名: PGD2SA
分子式: C23H39NO6
分子量: 425.6
纯度: >98%
溶解度: DMF: 25 mg/ml,DMSO: 25 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 5 mg/ml
储存: Store at -20°C
库存: 现货

Background

2-Arachidonyl glycerol (2-AG) exhibits cannabinoid (CB) agonist activity at the CB1 receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor. 2-AG can also be sequentially metabolized by COX-2 and specific PG synthases to form PG 2-glyceryl esters. In activated RAW 264.7 cells, PGD2 2-glyceryl ester is the primary product of 2-AG metabolism in the COX pathway. PGD2 serinol amide (PGD2-SA) is a stable analog of PGD2 2-glyceryl ester. Unlike PGD2 2-glyceryl ester and other fatty acyl 2-glyceryl esters, PGD2-SA will not isomerize to the less active primary (1-glyceryl) ester. The biological activity of PGD2-SA has not yet been determined.