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  • Prostaglandin E2-1-glyceryl ester
Prostaglandin E2-1-glyceryl ester的可视化放大

Prostaglandin E2-1-glyceryl ester

A product of 2-AG incubation with COX-2 and specific PGH2 isomerases

原价
¥1487-11825
价格
1190-9460
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  • 库存: 现货
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  • 货号: ajci73678
  • CAS: 37497-47-5
  • 别名: PGE21glyceryl ester
  • 分子式: C23H38O7
  • 分子量: 426.6
  • 纯度: >98%
  • 溶解度: DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 100 μ g/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

2-Arachidonoyl glycerol has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures and isolated enzyme preparations results in prostaglandin glycerol ester formation. The biosynthesis of PGH, PGD, PGE, PGF, and Thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of these prostaglandin products has been investigated, little is known about their intrinsic biological activity.

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