Prostaglandin E2-1-glyceryl ester

A product of 2-AG incubation with COX-2 and specific PGH2 isomerases

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库存: 现货

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1mg

￥1487.00

1190.00

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5mg

￥6650.00

5320.00

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10mg

￥11825.00

9460.00

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货号: ajci73678
CAS: 37497-47-5
别名: PGE21glyceryl ester
分子式: C23H38O7
分子量: 426.6
纯度: >98%
溶解度: DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 100 μ g/ml
储存: Store at -20°C
库存: 现货

Background

2-Arachidonoyl glycerol has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures and isolated enzyme preparations results in prostaglandin glycerol ester formation. The biosynthesis of PGH, PGD, PGE, PGF, and Thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of these prostaglandin products has been investigated, little is known about their intrinsic biological activity.