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  • Rp-8-bromo-Cyclic AMPS (sodium salt)
Rp-8-bromo-Cyclic AMPS (sodium salt)的可视化放大

Rp-8-bromo-Cyclic AMPS (sodium salt)

An antagonist of cAMP-dependent PKAs

原价
¥3062-24075
价格
2450-19260
Rp-8-bromo-Cyclic AMPS (sodium salt)的二维码

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  • 库存: 现货
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  • 货号: ajci73946
  • CAS: 925456-59-3
  • 别名: 8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer, Rp-8-BrcAMPS, Rp-8-bromocAMPS
  • 分子式: C10H10BrN5O5PS ?Na
  • 分子量: 446.1
  • 纯度: >98%
  • 溶解度: DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 0.5 mg/ml,PBS (pH 7.2): 10 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II from bovine heart.

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