Sultriecin
A fungal metabolite
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包装价格促销价数量
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500ug￥4500.003600.00- +
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2.5mg￥18937.0015150.00- +
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- 货号: ajci74188
- CAS: 131774-59-9
- 别名: BU-3285T, Phostriecin
- 分子式: C23H34O8P?Na
- 分子量: 492.5
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
Sultriecin is a fungal metabolite originally isolated from S. roseiscleroticus. It is active against a panel of 15 fungal strains (MICs = 0.8-50 μg/ml). Sultriecin is cytotoxic to B16/F10, HCT116, Moser, P388, A549, and K562 cancer cells (IC50s = 37.7, 1.92, 0.85, 3.8, 4.14, and 0.67 μg/ml, respectively). It also inhibits RNA and protein synthesis in L1210 leukemia cells (IC50s = 5.5 and 2.4 μg/ml, respectively). Sultriecin (0.1-10 mg/kg) increases survival time in a B16/F10 syngeneic mouse melanoma model and a P388 murine leukemia model.
