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A hydroquinone ansamycin antibiotic
TAN 420C is a hydroquinone ansamycin antibiotic originally isolated from Streptomyces. It exhibits antibacterial activity against B. brevis and M. flavus (MICs = 50 and 25 μg/mL, respectively). Additionally, it inhibits proliferation in the lymphocytic leukemia cell lines P388 and KB (ED50s = 0.34 and 3.49 μg/mL, respectively).
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