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  • Taurolithocholic Acid (sodium salt)
Taurolithocholic Acid (sodium salt)的可视化放大

Taurolithocholic Acid (sodium salt)

A taurine-conjugated form of lithocholic acid

原价
￥350-1150
价格
￥ 280-920
Taurolithocholic Acid (sodium salt)的二维码

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  • 库存: 现货
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  • 货号: ajci74234
  • CAS: 6042-32-6
  • 别名: 牛磺石胆酸钠
  • 分子式: C26H44NO5S?Na
  • 分子量: 505.7
  • 纯度: >98%
  • 溶解度: DMF: 25 mg/ml,DMSO: 20 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Taurolithocholic acid (TLCA) is a taurine-conjugated form of the secondary bile acid lithocholic acid . TLCA (75 μM) increases caspase-3 and -7 activity in Hep3B cells transfected with sodium taurocholate cotransporting peptide (NTCP), but not nontransfected Hep3B cells. It has been used to induce cholestasis in ex vivo and in vivo animal models of hepatocellular cholestasis. Serum levels of TLCA increase approximately 5-fold in within two hours during an oral lipid tolerance test in humans.

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