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Benzquinamide(P2647)是一种止吐剂,并可以与α2A,α2B,以及α2C肾上腺素能受体(α2-AR)结合,Ki值分别为1,365,691和545nM。
Benzquinamide (P2647) is an antiemetic which can bind to the α2A, α2B, and α2C adrenergic receptors (α2-AR) with Ki values of 1,365, 691, and 545 nM, respectively.
[1]. Elisabet Gregori-Puigjané, et al. Identifying mechanism-of-action targets for drugs and probes. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28): 11178-11183. doi: 10.1073/pnas.1204524109
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