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None-deuterium-VX-984是VX-984的非氘代形式。VX-984是一种ATP竞争性的DNA-PKcs抑制剂。
None-deuterium-VX-984 is the non-deuterated form of VX-984. VX-984 is an a ATP-competitive DNA-PKcs inhibitor.
[1]. Timme CR, et al. The DNA-PK Inhibitor VX-984 Enhances the Radiosensitivity of Glioblastoma Cells Grown In Vitroand as Orthotopic Xenografts. Mol Cancer Ther. 2018 Jun;17(6):1207-1216.
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