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  • Deschloroclozapine
Deschloroclozapine的可视化放大

Deschloroclozapine

Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respecti

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¥1212-7012
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  • 货号: ajce45786
  • CAS: 1977-07-7
  • 别名: 氯氮平杂质
  • 分子式: C18H20N4
  • 分子量: 292.38
  • 纯度: >98%
  • 溶解度: DMSO: 100 mg/mL (342.02 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.


[1] Hu F, et al. Eur J Med Chem. 2021 Mar 5;213:113047.

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