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- GABA Receptor
- CP-409092
CP-409092
CP-409092是GABA(A)的部分激动剂，主要用于抗焦虑研究。
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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包装价格促销价数量
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1mg￥13550.0010840.00- +
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5mg￥27112.0021690.00- +
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10mg￥46087.0036870.00- +
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20mg￥81387.0065110.00- +
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- 货号: ajce46346
- CAS: 194098-25-4
- 别名:
- 分子式: C17H19N3O2
- 分子量: 297.35
- 纯度: ＞98%
- 溶解度: DMSO: 41.67 mg/mL (140.14 mM)
- 储存: Store at -20°C
- 库存: 现货
Background
CP-409092 is a GABA(A) partial agonist, used for the treatment of anxiety.
The pharmacokinetics of CP-409,092 following single intravenous and oral doses of 4 and 15 mg/kg, respectively, are characterized by high clearance of 169+ or -18 mL/min/kg, a volume of distribution of 8.99+ or -1.46 L/kg, and an oral bioavailability of 2.9%+ or -3%. Following oral administration of 100 mg/kg [14C]CP-409,092, the total recovery is 89.1%+ or -3.2% for male rats and 89.3%+ or -0.58% for female rats[1].
[1]. Kamel A, et al. Metabolism, pharmacokinetics and excretion of the GABA(A) receptor partial agonist [(14)C]CP-409,092 in rats. Xenobiotica. 2010 Jun;40(6):400-14.
