A synthetic isoflavone
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7-Methoxyisoflavone is a synthetic isoflavone and an isomer of 7-methoxyflavone .1,2 It inhibits mitosis induced by concanavalin A in human peripheral blood mononuclear cells (PBMCs) with an IC50 value of 1.36 ?g/ml.1 7-Methoxyisoflavone (10, 20, and 40 ?M) inhibits the growth of HCT116 colon cancer cells in a concentration-dependent manner.2
1.Hirano, T., Oka, K., Kawashima, E., et al.Effects of synthetic and naturally occurring flavonoids on mitogen-induced proliferation of human peripheral-blood lymphocytesLife Sci.45(15)1407-1411(1989) 2.Hyun, J., Shin, S.Y., So, K.M., et al.Isoflavones inhibit the clonogenicity of human colon cancer cellsBioorg. Med. Chem. Lett.22(8)2664-2669(2012)
Dorsomorphin (Compound C) 2HCl
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