CMI977是一种有效的5-Lipoxygenase(5-LO)抑制剂。
货号：ajce48164
CAS：175212-04-1
分子式：C16H19FN2O4
分子量：322.33
纯度：98%
存储：Store at -20°C
库存：现货
Background:
CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor.
CMI977 is a potent 5-lipoxygenase (5-LO) inhibitor that intervenes in the production of leukotrienes and is presently being developed for the treatment of chronic asthma. It is a single enantiomer with an all-trans (2S,5S) configuration. Of the four isomers of CMI977, the S,S isomer is found to have the best biological activity and is selected for further development.
[1]. Xiong Cai, et al. Synthesis of CMI-977, a Potent 5-Lipoxygenase Inhibitor. Org. Proc. Res. Dev., 1999, 3 (1), pp 73-76.
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