Trovirdine (LY300046)

Trovirdine (LY300046) 在使用异聚引物/模板（寡-DNA/核糖体 RNA）和 dGTP 作为底物时抑制 HIV-1 RT，IC50 为 7 nM。

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
5mg

￥762.00

610.00

- +
10mg

￥1300.00

1040.00

- +
25mg

￥2725.00

2180.00

- +
50mg

￥4850.00

3880.00

- +
100mg

￥8100.00

6480.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

Background

Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate.IC50 value: 7 nMTarget: HIV-1Trovirdine is currently in phase I clinical trials for potential use in thetreatment of AIDS.

[1]. Zhang, H. et al. Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethylthiazolyl thiourea derivatives trovirdine and MSC-127. [2]. Cantrell, A.S. et al. Phenethylthiazolylthiourea (PETT) compounds as a newclass of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.