Ceftizoxime sodium (SKF-88373)

A cephalosporin antibiotic

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库存: 现货

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50mg

￥537.00

430.00

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100mg

￥862.00

690.00

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货号: ajce48602
CAS: 68401-82-1
别名: 头孢唑肟钠; SKF-88373
分子式: C13H12N5NaO5S2
分子量: 405.38
纯度: >98%
溶解度: DMSO : 15 mg/mL (37.00 mM)
储存: Store at -20°C,unstable in solution, ready to use.
库存: 现货

Background

Ceftizoxime is a cephalosporin antibiotic.¹ Ceftizoxime is active against clinical isolates of the Gram-positive bacteria S. aureus, S. pyogenes, and S. epidermidis (IC₅₀s = 1.56, ≤0.025, and 0.78 ?g/ml, respectively), as well as clinical isolates of the Gram-negative bacteria E. coli, K. pneumoniae, and P. mirabilis (IC₅₀s = 0.1, ≤0.025, and ≤0.025 ?g/ml, respectively). It is protective against S. aureus, E. coli, P. mirabilis, or P. vulgaris infection in mice (ED₅₀s = 4.03, 0.02, 0.255, and 0.038 mg/kg, respectively).² Formulations containing ceftizoxime have been used in the treatment of a variety of bacterial infections.

1.Kamimura, T., Matsumoto, Y., Okada, N., et al.Ceftizoxime (FK 749), a new parenteral cephalosporin: In vitro and in vivo antibacterial activitiesAntimicrob. Agents Chemother.16(5)540-548(1979) 2.Nishida, M., Kamimura, T., Okada, N., et al.Comparison of antibacterial activity of a new cephalosporin, ceftizoxime (FK 749) with other cephalosporin antibioticsJ. Antibiot. (Tokyo)32(12)1319-1327(1979)