Hetacillin

A prodrug form of ampicillin

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库存: 现货

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1mg

￥650.00

520.00

- +
5mg

￥1975.00

1580.00

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10mg

￥3300.00

2640.00

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Background

Hetacillin is a prodrug form of the broad-spectrum antibiotic ampicillin .¹ It is converted to ampicillin via hydrolysis. Hetacillin is active against several bacteria, including E. coli, S. typhimurium, S. flexneri, H. influenzae, and S. pneumoniae (MICs = 2.5, 1.25, 2.5, 0.5, and 0.05 ?g/ml, respectively). Intramammary administration of hetacillin increases the cure rate of bacterial infections in dairy cows.² Formulations containing hetacillin have been used in the treatment of bovine mastitis.

1.Sutherland, R., and Robinson, O.P.W.Laboratory and pharmacological studies in man with hetacillin and ampicillinBr. Med. J.2(5555)804-808(1967) 2.Vasquez, A.K., Nydam, D.V., Capel, M.B., et al.Randomized noninferiority trial comparing 2 commercial intramammary antibiotics for the treatment of nonsevere clinical mastitis in dairy cowsJ. Dairy Sci.99(10)8267-8281(2016)