三（4-氨基苯基）甲烷（Leucopararosaniline）是一种三苯基甲烷染料。
Tris(4-aminophenyl)methane is a triphenylmethane dye. Tris(4-aminophenyl)methane is a weak HCV helicase inhibitor.
Tris(4-aminophenyl)methane (Compound 8) shows weak HCV helicase inhibition (30% inhibition at 100 μM)[1]. To preserve RNA in a biological sample for analysis, the sample is incubated with an RNA preservative capable of precipitating RNA in an aqueous solution, such as a triphenylmethane dye (e.g., methyl green, crystal violet, pararosaniline, or Tris(4-aminophenyl)methane), cresyl violet, or cobalt ions. RNA preservation may be used in an immunostaining assay and other histochemical methods[2].
[1]. Chen CS, et al. Structure-based discovery of triphenylmethane derivatives as inhibitors of hepatitis C virushelicase. J Med Chem. 2009 May 14;52(9):2716-23.
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