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- 5-HT Receptor
- 5-HT2 antagonist 1
5-HT2 antagonist 1
5-HT2antagonist1是一种有效的5-HT2receptor拮抗剂，同时对α1adrenoceptor有微弱地抑制作用。
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包装价格促销价数量
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1mg￥15250.0012200.00- +
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5mg￥34325.0027460.00- +
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10mg￥58387.0046710.00- +
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20mg￥103012.0082410.00- +
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- 货号: ajce49552
- CAS: 191592-09-3
- 别名:
- 分子式: C22H29FN4O2
- 分子量: 400.49
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
5-HT2 antagonist 1 is a potent antagonist of 5-HT2 receptor, with weak α1 adrenoceptor blocking activity.
5-HT2 antagonist 1 shows 45%, 88%, 93% inhibition of 10 μM erotonin-induced contraction at 10 nM, 100 nM, 1000 nM, respectively, in guinea pig mesentcric artery. 5-HT2 antagonist 1 causes 1% and 10% inhibition of 10 μM norepinephrine-induced contraction at 10 and 100 nM, respectively, in guinea pig aorta[1].
[1]. Mizuno A, et al. Synthesis and serotonin 2 (5-HT2) receptor antagonist activity of 5-aminoalkyl-substituted pyrrolo[3,2-c]azepines and related compounds. Chem Pharm Bull (Tokyo). 2000 May;48(5):623-35.
