现货大促销,价格低至8折起,量大更优惠,详细咨询客服
全部分类
全部分类
  • Fotemustine (S10036)
Fotemustine (S10036)的可视化放大

Fotemustine (S10036)

Fotemustine是一种DNA烷化剂(DNAalkylator),具有抗肿瘤作用。

原价
¥637-2700
价格
510-2160
Fotemustine (S10036)的二维码

所有产品仅用于科学研究,我们不为任何个人用途提供产品和服务

询价有惊喜,量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajce49896
  • CAS: 92118-27-9
  • 别名: 福莫司汀
  • 分子式: C9H19ClN3O5P
  • 分子量: 315.69
  • 纯度: >98%
  • 溶解度: DMSO : ≥ 3.2 mg/mL (10.14 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Fotemustine is a DNA-alkylating agent, with antitumor activity.


Fotemustine is a DNA-alkylating agent. Fotemustine (800 μM) decreases GSH and intracellular GSSG levels but increases the extracellular GSSG-levels rapidly in isolated rat hepatocytes[1]. Fotemustine shows inhibitory effect on several tumor cell lines, with IC50s ranging form 0.05 to 0.18 mM[2].


[1]. Brakenhoff JP, et al. Molecular mechanisms of toxic effects of fotemustine in rat hepatocytes and subcellular rat liver fractions. Carcinogenesis. 1996 Apr;17(4):715-24. [2]. Merlin JL, et al. Enhancement of fotemustine (Muphoran) cytotoxicity by amifostine in malignant melanoma cell lines. Anticancer Drugs. 2002 Feb;13(2):141-7.

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服