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PNU-248686A是一种新型的基质金属蛋白酶(MMP)抑制剂。
PNU-248686A is a novel matrix metalloproteinase (MMP) inhibitor.
PNU-248686A is an orally active matrix metalloproteinase (MMP) inhibitor developed for the treatment of solid tumors over-expressing MMPs[1].
[1]. Frigerio E, et al. Determination of PNU-248686A, a novel matrix metalloproteinase inhibitor, in human plasma by liquid chromatography-tandem mass spectrometry, following protein precipitation in the 96-well plate format. J Chromatogr A. 2003 Feb 14;987(1-2):249-56.
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