Adrenocorticotropic Hormone (ACTH) (18-39), human (CLIP (human))

A peptide fragment of ACTH

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1mg

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1210.00

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5mg

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货号: ajce51818
CAS: 53917-42-3
别名: CLIP (human)
分子式: C112H165N27O36
分子量: 2465.67
纯度: >98%
溶解度: DMF: 2.5mg/mL,DMSO: 5mg/mL,PBS (pH 7.2): 5mg/mL
储存: Store at -20°C
库存: 现货

Background

Adrenocorticotropic hormone (ACTH) (18-39) is a C-terminal peptide fragment of ACTH, a peptide hormone found in the brain that is involved in the biological stress response.¹ It is produced via processing of ACTH in the intermediate lobe of the pituitary gland.^1,2 ACTH (18-39) increases cumulative food intake in fasted, but not fed, rats when administered intracerebroventricularly at a dose of 2.5 nmol/animal.²

1.Strand, F.L., Lee, S.J., Zuccarelli, L.A., et al.Non-corticotropic ACTH peptides modulate nerve development and regenerationRev. Neurosci.4(4)321-363(1993) 2.Al-Barazanji, K.A., Miller, J.E., Rice, S.Q.J., et al.C-terminal fragments of ACTH stimulate feeding in fasted ratsHorm. Metab. Res.33(8)480-485(2001)