N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ)
N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ) 是一种有效的烯二炔抗肿瘤抗生素。
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包装价格促销价数量
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1mg￥19062.0015250.00- +
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5mg￥63587.0050870.00- +
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- 货号: ajce52074
- CAS: 108212-76-6
- 别名: N-乙酰-凯立霉素,N-Acetyl-Calicheamicin γ; N-Acetyl-γ-calicheamicin
- 分子式: C57H76IN3O22S4
- 分子量: 1410.39
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
N-Acetyl-Calicheamicin is a potent enediyne antitumor antibiotic. Target: AntibacterialN-Acetyl-Calicheamicin is a a derivative of Calicheamicin. Calicheamicin is a naturally occurring hydrophobic enediyne antibiotic that was isolated from the actinomycete Micromonospora echinospora calichensis. Calicheamicin can interfere with biological processes not simply by cleaving free DNA but also by displacing a DNA-binding protein through competition or modulation of DNA structure.
[1]. Stasi R, et al. Gemtuzumab ozogamicin in the treatment of acute myeloid leukemia. Cancer Treat Rev. 2008 Feb;34(1):49-60.
