An acaricide
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Bifenazate is a carbazate acaricide that provides 100% control of mites when used at a concentration of 25 ppm.1 It acts as a positive allosteric modulator of GABA receptors containing the resistance to dieldrin (Rdl) subunit homolog TuGABAR in T. urticae (spider mites), shifting the GABA-induced response from an EC50 value of 24.8 to 4.83 ?M when used at a concentration of 30 ?M.2 Formulations containing bifenazate have been used for the control of mites and for pesticide detection.
1.Dekeyser, M.A., McDonald, P.T., and Angle, G.W., Jr.The discovery of bifenazate, a novel carbazate acaricideChimia57(11)702-704(2003) 2.Hiragaki, S., Kobayashi, T., Ochiai, N., et al.A novel action of highly specific acaricide; bifenazate as a synergist for a GABA-gated chloride channel of Tetranychus urticae [Acari: Tetranychidae]Neurotoxicology33(3)307-313(2012)
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