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  • C25-140
C25-140的可视化放大

C25-140

C25-140 is a small-molecule inhibitor of TRAF6-Ubc13 interaction. C25-140 directly binds to TRAF6, thereby blocking the interaction of TRAF6 with Ubc13, and as a consequence lowers TRAF6 activity. C25-140 impedes NF-κB activation in various immune and inf

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¥2287-21375
价格
1830-17100
C25-140的二维码

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  • 货号: ajce53268
  • CAS: 1358099-18-9
  • 别名:
  • 分子式: C26H31N7O
  • 分子量: 457.57
  • 纯度: >98%
  • 溶解度: DMSO : ≥ 130 mg/mL (284.11 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

C25-140 is a small-molecule inhibitor of TRAF6-Ubc13 interaction. C25-140 directly binds to TRAF6, thereby blocking the interaction of TRAF6 with Ubc13, and as a consequence lowers TRAF6 activity. C25-140 impedes NF-κB activation in various immune and inflammatory signaling pathways also in primary human and murine cells.


[1] Brenke JK, et al. J Biol Chem. 2018 Aug 24;293(34):13191-13203.

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