IWP-O1

IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.

原价

￥1300-15487

价格

￥ 1040-12390

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产品引用

Cell.Cell host & microbe.November 8, 2023
Cell . MOLECULAR PLANT . 1 February 2023
Cell . Immunity . August 10, 2021
Nature Communications.1413 (2022)
ACS . Nano Lett . April 10, 2023

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货号: ajce53498
CAS: 2074607-48-8
别名:
分子式: C26H20N6O
分子量: 432.48
纯度: >98%
溶解度: DMSO : 125 mg/mL (289.03 mM);Water : < 0.1 mg/mL (insoluble)
储存: 4°C, protect from light
库存: 现货

Background

IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.

IWP-O1 has significantly improved metabolic stability[1].

[1] You L, et al. Bioorg Med Chem Lett. 2016, 26(24):5891-5895.

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