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SAHAchloroalkaneT1是一种通过Vorinostat(SAHA)和氯代烷烃T1链结合的捕获标记。
SAHA chloroalkane T1 is a chloroalkane capture tag by tethering Vorinostat (SAHA) and a chloroalkane tag T1[1].
SAHA chloroalkane T1 minimally affects SAHA potency in K-562 cells, allowing binding interactions with the targets to occur under conditions relevant to the desired cellular phenotype[1].
[1]. Ohana RF, et al. Deciphering the Cellular Targets of Bioactive Compounds Using a Chloroalkane Capture Tag. ACS Chem Biol. 2015 Oct 16;10(10):2316-24.
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