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  • SPP-86
SPP-86的可视化放大

SPP-86

SPP-86, a potent and selective cell permeable inhibitor of rearranged during transfection (RET) tyrosine kinase with an IC50 of 8 nM, inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen re

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￥1300-1300
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￥ 1040-1040
SPP-86的二维码

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  • 库存: 现货
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  • 货号: ajce53860
  • CAS: 1357349-91-7
  • 别名:
  • 分子式: C16H15N5
  • 分子量: 277.32
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

SPP-86, a potent and selective cell permeable inhibitor of rearranged during transfection (RET) tyrosine kinase with an IC50 of 8 nM, inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells.


[1] Alao JP, et al. BMC Cancer. 2014 Nov 20;14:853.

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