UBCS039
UBCS039 is the first synthetic SIRT6 activator with EC50 of 38 μM,induces a time-dependent activation of autophagy in several human tumor cell lines.
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
-
包装价格促销价数量
-
5mg￥1962.001570.00- +
-
10mg￥3050.002440.00- +
-
25mg￥6150.004920.00- +
-
50mg￥10362.008290.00- +
-
100mg￥17625.0014100.00- +
已选
0
种
0
瓶
金额:
￥0.00
首页
收藏
- 货号: ajce53940
- CAS: 358721-70-7
- 别名:
- 分子式: C16H13N3
- 分子量: 247.29
- 纯度: ＞98%
- 溶解度: DMSO : 125 mg/mL (505.48 mM)
- 储存: Store at -20°C
- 库存: 现货
Background
UBCS039 is the first synthetic SIRT6 activator with EC50 of 38 μM,induces a time-dependent activation of autophagy in several human tumor cell lines.
UBCS039 induces deacetylation of SIRT6-targeted histone H3 sites in human cancer cells.UBCS039 leads to autophagosome accumulation and induces autophagic flux in human cancer cells.UBCS039 also induces autophagy-associated cell death.[1]
[1] You W,et al.Angew Chem Int Ed Engl. 2017 19;56(4):1007-1011.
