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  • N6-Ethyladenosine
N6-Ethyladenosine的可视化放大

N6-Ethyladenosine

An adenosine A1 and A3 receptor agonist

原价
¥1625-4850
价格
1300-3880
N6-Ethyladenosine的二维码

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  • 货号: ajce54084
  • CAS: 14357-08-5
  • 别名: NSC 516603
  • 分子式: C12H17N5O4
  • 分子量: 295.29
  • 纯度: >98%
  • 溶解度: DMSO : ≥ 83.33 mg/mL (282.20 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

N6-Ethyladenosine is an adenosine A1 and A3 receptor agonist.1 It binds selectively to rat adenosine A1 and human adenosine A3 receptors over rat adenosine A2A and A3 receptors (Kis = 4.9, 4.7, 8,900 and 1,050 nM, respectively, for the recombinant receptors in CHO cells). N6-Ethyladenosine completely inhibits forskolin-induced cAMP accumulation in CHO cells expressing the human recombinant adenosine A3 receptor when used at a concentration of 10 ?M.


1.Gao, Z.-G., Blaustein, J.B., Gross, A.S., et al.N6-Substituted adenosine derivatives: Selectivity, efficacy, and species differences at A3 adenosine receptorsBiochem. Pharmacol.65(10)1675-1684(2003)

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