An inhibitor of PD-1 signaling
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PD-1-IN-17 is an inhibitor of the programmed cell death protein 1 (PD-1) signaling pathway.1 It reverses inhibition of isolated mouse splenocyte proliferation induced by PD-1 ligand (PD-L1) when used at a concentration of 100 nM.
1.Sasikumar, P.G.N., Ramachandra, M., and Naremaddepalli, S.S.S.1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives as immunomodulators(2015)