(-)-Corynoxidine 分离自延胡索 Corydalis speciosa，是一种乙酰胆碱酯酶 acetylcholinesterase 抑制剂，IC50 值为 89.0 μM。(-)-Corynoxidine 对金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌菌株有不同程度的抗菌活性。
(-)-Corynoxidine is an acetylcholinesterase inhibitor with an IC50 value of 89.0 μM, isolated from the aerial parts of Corydalis speciosa[1].(-)-Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains in different degrees[2]. IC50: 89.0 μM (acetylcholinesterase)[1]
[1]. Kim DK, et al. Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa. Arch Pharm Res. 2004 Nov;27(11):1127-31. [2]. Yang DL, et al. A new antibacterial denitroaristolochic acid from the tubers of Stephania succifera. J Asian Nat Prod Res. 2013;15(3):315-8.
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