α-Bisabolol

A sesquiterpene alcohol with anticancer activity

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500mg

￥425.00

340.00

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1g

￥675.00

540.00

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货号: ajce54852
CAS: 515-69-5
别名: alpha-红没药醇
分子式: C15H26O
分子量: 222.37
纯度: >98%
溶解度: DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 5 mg/ml
储存: Store at -20°C
库存: 现货

Background

(±)-α-Bisabolol is a sesquiterpene alcohol that has been found in M. chamomilla and has anticancer activity.^1,2 It induces apoptosis in, and is cytotoxic to, T67 and U87 glioma cells when used at concentrations ranging from 3.5 to 10 ?M.¹ (±)-α-Bisabolol is also cytotoxic to primary acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) cells (IC₅₀s = 14-65 ?M).²

1.Cavalieri, E., Mariotto, S., Fabrizi, C., et al.ɑ-Bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cellsBiochem. Biophys. Res. Commun.315(3)589-594(2004) 2.Cavalieri, E., Rigo, A., Bonifacio, M., et al.Pro-apoptotic activity of ɑ-bisabolol in preclinical models of primary human acute leukemia cellsJ. Transl. Med.945(2011)