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  • Btk inhibitor 1
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Btk inhibitor 1

(Rac)-IBT6A (BTK inhibitor 1) is a racemate of IBT6A and an impurity of Ibrutinib, which is a Btk inhibitor (IC50=0.5 nM), and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.

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0-16690
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  • 货号: ajce55364
  • CAS: 1412418-47-3
  • 别名:
  • 分子式: C22H22N6O
  • 分子量: 386.45
  • 纯度: >98%
  • 溶解度: DMSO: 50 mg/mL (129.38 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

(Rac)-IBT6A (BTK inhibitor 1) is a racemate of IBT6A and an impurity of Ibrutinib, which is a Btk inhibitor (IC50=0.5 nM), and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.


[1] Somana Siva Prasad, et al. R. J. M. 2019 (July), 12(3): 1434 - 45 [2] Honigberg LA, et al. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.

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