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Cauloside C

A triterpenoid saponin with diverse biological activities

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Cauloside C的二维码
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  • 货号: ajce55474
  • CAS: 20853-58-1
  • 别名: 葳岩仙皂苷 C
  • 分子式: C41H66O13
  • 分子量: 766.95
  • 纯度: >98%
  • 溶解度: DMF: 20 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 15 mg/ml,Ethanol: 5 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Hederoside D2 is a triterpenoid saponin originally isolated from C. robustum rhizome and roots and has diverse biological activities.1,2 It induces potassium release and hemolysis in mouse erythrocytes in a pH-dependent manner when used at a concentration of 10 μg/ml.2 Hederoside D2 is cytotoxic to N1E-115 neuroblastoma cells at low pH. It induces proliferation of human embryonic fibroblasts in acidic medium, an effect that can be blocked by the calcium channel blockers verapamil , diltiazem, and nitrendipine .


1.Murakami, T., Nagasawa, M., Urayama, S., et al.New triterpenoid saponins in the rhizome and roots of Caulophyllum robustumYakugaku Zasshi88(3)321-324(1968) 2.Likhatskaya, G.N., Aminin, D.L., Agafonova, I.G., et al.The pH-dependent channels formed by cauloside CAdvances in Experimental Medicine and Biology404239-249(1996)

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