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- Cnidicin
Cnidicin
Cnidicin 是一种来自 Angelica koreana 根的香豆素，可抑制肥大细胞脱颗粒和 RAW 264.7 细胞产生一氧化氮 (NO).
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- 货号: ajce55678
- CAS: 14348-21-1
- 别名: 蛇床素
- 分子式: C21H22O5
- 分子量: 354.4
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
Cnidicin is a coumarin from the root of Angelica koreana, and inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells[1].
Cnidicin shows a significant inhibition upon the release of beta-hexosaminidase from the cultured RBL-2H3 cells in a dose dependent manner (IC50= 25 μM) and upon the nitric oxide production from the activated RAW264.7 cells (IC50=7.5 μM)[1].
[1]. Ryu SY, et al. Cnidicin, a coumarin, from the root of Angelica koreana, inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells. Planta Med. 2001 Mar;67(2):172-4.
