安捷凯生物医药
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  • Deruxtecan
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Deruxtecan

Deruxtecan is an ADC drug-linker conjugate composed of the cleavable glycine–glycine–phenylalanine–glycine tetrapeptide-based linker, a self-immolative amino methylene spacer, and a novel topoisomerase 1 inhibitor payload that is a derivative of exatecan

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Deruxtecan的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 5mg
    ￥2537.00
    2030.00
    - +
  • 10mg
    ￥3387.00
    2710.00
    - +
  • 50mg
    ￥14125.00
    11300.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajce55922
  • CAS: 1599440-13-7
  • 别名:
  • 分子式: C52H56FN9O13
  • 分子量: 1034.05
  • 纯度: >98%
  • 溶解度: DMSO: ≥ 50 mg/mL (48.35 mM); Water: < 0.1 mg/mL (insoluble)
  • 储存: Store at -20°C,protect from light，stored under nitrogen
  • 库存: 现货

Background

Deruxtecan is an ADC drug-linker conjugate composed of the cleavable glycine–glycine–phenylalanine–glycine tetrapeptide-based linker, a self-immolative amino methylene spacer, and a novel topoisomerase 1 inhibitor payload that is a derivative of exatecan (DX-8951).


[1] A Yver, et al. Ann Oncol . 2020 Mar;31(3):430-434.

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