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  2. Antibody-drug Conjugate/ADC Related
  3. Deruxtecan
  • Deruxtecan
Deruxtecan的可视化放大

Deruxtecan

Deruxtecan is an ADC drug-linker conjugate composed of the cleavable glycine–glycine–phenylalanine–glycine tetrapeptide-based linker, a self-immolative amino methylene spacer, and a novel topoisomerase 1 inhibitor payload that is a derivative of exatecan

原价
￥2537-14125
价格
￥ 2030-11300
Deruxtecan的二维码

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  • 库存: 现货
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  • 货号: ajce55922
  • CAS: 1599440-13-7
  • 别名:
  • 分子式: C52H56FN9O13
  • 分子量: 1034.05
  • 纯度: >98%
  • 溶解度: DMSO: ≥ 50 mg/mL (48.35 mM); Water: < 0.1 mg/mL (insoluble)
  • 储存: Store at -20°C,protect from light，stored under nitrogen
  • 库存: 现货

Background

Deruxtecan is an ADC drug-linker conjugate composed of the cleavable glycine–glycine–phenylalanine–glycine tetrapeptide-based linker, a self-immolative amino methylene spacer, and a novel topoisomerase 1 inhibitor payload that is a derivative of exatecan (DX-8951).


[1] A Yver, et al. Ann Oncol . 2020 Mar;31(3):430-434.

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