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  • Ganoderic acid B
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Ganoderic acid B

A triterpenoid with diverse biological activities

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Ganoderic acid B的二维码
  • 库存: 现货
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  • 1mg
    ¥1625.00
    1300.00
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    ¥4037.00
    3230.00
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  • 货号: ajce56474
  • CAS: 81907-61-1
  • 别名: 灵芝酸B
  • 分子式: C30H44O7
  • 分子量: 516.67
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

Ganoderic acid B is a triterpenoid that has been found in G. lucidum and has diverse biological activities.1,2,3 It inhibits HIV-1 protease with an IC50 value of 0.17 mM.1 Ganoderic acid B is cytotoxic to HepG2 and Caco-2 cells (IC50s = 0.65 and 0.36 mg/ml, respectively).2 It inhibits acetic acid-induced writhing in mice by 48.3% when administered at a dose of 5 mg/kg.3


1.El-Mekkawy, S., Meselhy, M.R., Nakamura, N., et al.Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidumPhytochemistry49(6)1651-1657(1998) 2.Ruan, W., Lim, A.H.H., Huang, L.G., et al.Extraction optimisation and isolation of triterpenoids from Ganoderma lucidum and their effect on human carcinoma cell growthNat. Prod. Res.28(24)2264-2272(2014) 3.Koyama, K., Imaizumi, T., Akiba, M., et al.Antinociceptive components of Ganoderma lucidumPlanta Med.63(3)224-227(1997)

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