Ginsenoside F4

Ginsenoside F4 (GF4)，人参皂甙，从三七或红参中分离。Ginsenoside F4 (GF4) 通过诱导凋亡 (apoptosis) 对人淋巴细胞瘤 JK 细胞具有抑制作用。Ginsenoside F4 (GF4) 抑制 IL-1β 处理的软骨细胞中基质金属蛋白酶 13 (MMP 13) 的表达，阻断兔软骨组织培养中的软骨损坏，具有防止病变组织的软骨胶原基质分解的治疗潜力。

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1mg

￥1637.00

1310.00

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5mg

￥4925.00

3940.00

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Background

Ginsenoside F4 (GF4), ginseng saponinis, isolated from notoginseng or red ginseng. Ginsenoside F4 (GF4) has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis[1].Ginsenoside F4 (GF4) inhibits matrix metalloproteinase 13 (MMP 13) expression in IL-1β-treated chondrocytes and blocks cartilage breakdown in rabbit cartilage tissue culture, shows therapeutic potential for preventing cartilage collagen matrix breakdown in diseased tissues[2].

[1]. Chen B, et al. The apoptosis-inducing effect of ginsenoside F4 from steamed notoginseng on human lymphocytoma JK cells. Nat Prod Res. 2013;27(24):2351-4. [2]. Lee JH, et al. Ginsenosides from Korean red ginseng inhibit matrix metalloproteinase-13 expression in articular chondrocytes and prevent cartilage degradation. Eur J Pharmacol. 2014 Feb 5;724:145-51.