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  • MC-Val-Cit-PAB-dimethylDNA31
MC-Val-Cit-PAB-dimethylDNA31的可视化放大

MC-Val-Cit-PAB-dimethylDNA31

MC-Val-Cit-PAB-dimethylDNA31 是基于季铵的生物可逆连接,用于靶向递送,可以改善药代动力学和治疗指数。MC-Val-Cit-PAB-dimethylDNA31 用于体外和体内有效且稳定的抗体-药物偶联物 (antibody-drug conjugates) 以治疗各种疾病或病症。

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  • 货号: ajce57382
  • CAS: 1639352-06-9
  • 别名:
  • 分子式: C78H101N10O19
  • 分子量: 1482.69
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

MC-Val-Cit-PAB-dimethylDNA31 has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-dimethylDNA31 is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].



[1]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

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