Omadacycline tosylate

An aminomethylcycline antibiotic

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库存: 现货

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2mg

￥1712.00

1370.00

- +
5mg

￥2812.00

2250.00

- +
50mg

￥15887.00

12710.00

- +

已选 0 种 0 瓶

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货号: ajce57852
CAS: 1075240-43-5
别名: 奥马环素; PTK 0796 tosylate; Amadacycline tosylate
分子式: C36H48N4O10S
分子量: 728.85
纯度: >98%
溶解度: DMSO : 100mg/mL; Water : 100mg/mL
储存: 4°C, protect from light
库存: 现货

Background

Omadacycline is an aminomethylcycline antibiotic.¹ It is active against tetracycline-susceptible and -resistant strains of S. aureus, E. faecalis, E. faecium, S. pneumoniae, and E. coli, as well as β-hemolytic streptococci (MICs = ≤0.06-2 ?g/ml). Omadacycline increases survival in mouse models of systemic infection with tetracycline-sensitive and -resistant strains of S. pneumoniae, S. aureus, or E. coli (ED₅₀s = 0.3-3.34 mg/kg). Formulations containing omadacycline have been used in the treatment of community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI).

1.Macone, A.B., Caruso, B.K., Leahy, R.G., et al.In vitro and in vivo antibacterial activities of omadacycline, a novel aminomethylcyclineAntimicrob. Agents Chemother.58(2)1127-1135(2014)