Poricoic acid A is isolated from the surface layer of Poria cocos. Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis. Poricoic acid A also is a modulator of tryptophan hydroxy
Poricoic acid A is isolated from the surface layer of Poria cocos. Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis. Poricoic acid A also is a modulator of tryptophan hydroxylase-1 (TPH-1).
[1] Dan-Qian Chen, et al. Ther Adv Chronic Dis . 2019 Aug 14;10:2040622319869116. [2] Dan-Qian Chen, et al. Phytomedicine . 2020 Jul;72:153232. [3] Dan-Qian Chen, et al. Ther Adv Chronic Dis . 2020 Sep 30;11:2040622320962648.
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