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Pristinamycin IA

A macrolide antibiotic

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Pristinamycin IA的二维码
  • 库存: 现货
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  • 1mg
    ¥1100.00
    880.00
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  • 5mg
    ¥2825.00
    2260.00
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  • 10mg
    ¥4525.00
    3620.00
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  • 25mg
    ¥9175.00
    7340.00
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  • 50mg
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  • 货号: ajce58178
  • CAS: 3131-03-1
  • 别名: 普利霉素IA,Mikamycin B; Mikamycin IA
  • 分子式: C45H54N8O10
  • 分子量: 866.96
  • 纯度: >98%
  • 溶解度: DMSO: 33.33 mg/mL (38.44 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Streptogramin B is a macrolide antibiotic.1 It inhibits the growth of Clostridium, Peptostreptococcus, and Propionibacterium bacterial species (MIC90s = 2, 0.5, and 8 μg/ml, respectively).2 Streptogramin B inhibits protein synthesis by interacting with the 50S ribosome.1 Resistance to streptogramin B is conferred by erythromycin ribosome methylation (erm) genes, which code for methylases that methylate the 50S ribosome, interfering with streptogramin B binding.


1.Roberts, M.C., Sutcliffe, J., Courvalin, P., et al.Nomenclature for macrolide and macrolide-lincosamide-streptogramin B resistance determinantsAntimicrob. Agents Chemother.43(12)2823-2830(1999) 2.Laforest, H., Fourgeaud, M., Richet, H., et al.Comparative in vitro activities of pristinamycin, its components, and other antimicrobial agents against anaerobic bacteriaAntimicrob. Agents Chemother.32(7)1094-1096(1988)

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