PROTAC Linker 28
PROTAC Linker 28 是一种 PROTAC 连接桥，属于 alkyl chain类。PROTAC Linker 28 可用于合成一系列 PROTAC 分子。PROTAC 分子含有两个通过连接桥连接的不同配体; 一种是 E3 泛素连接酶配体，另一种是靶蛋白配体。PROTAC 利用细胞内泛素-蛋白酶体系统选择性降解靶蛋白。
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包装价格促销价数量
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100mg￥2571.001800.00- +
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250mg￥4285.003000.00- +
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500mg￥7500.000.00- +
- 货号: ajce58250
- CAS: 88986-89-4
- 别名: 1-(2-甲氧基乙氧基)丙-2-酮；1-(2-甲氧基乙氧基)丙-2-酮;1-(2-甲氧基乙氧基)-2-丙酮
- 分子式: C6H12O3
- 分子量: 132.16
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
PROTAC Linker 28 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 28 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. Alkyl/ether
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
