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  • Prulifloxacin
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Prulifloxacin

A prodrug from of ulifloxacin

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Prulifloxacin的二维码
  • 库存: 现货
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  • 100mg
    ¥812.00
    650.00
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  • 500mg
    ¥2437.00
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  • 1g
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  • 货号: ajce58282
  • CAS: 123447-62-1
  • 别名: 普卢利沙星; NM441
  • 分子式: C21H20FN3O6S
  • 分子量: 461.46
  • 纯度: >98%
  • 溶解度: DMSO: 12.5 mg/mL (27.09 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Prulifloxacin is a prodrug form of the fluoroquinolone antibiotic ulifloxacin.1 In vivo, prulifloxacin increases survival in mouse models of systemic S. aureus, S. pyogenes, S. pneumoniae, E. coli, K. pneumoniae, S. marcescens, or P. aeruginosa infection (ED50s = 0.35-23 mg/kg). It also increases survival in a mouse model of K. pneumoniae-induced respiratory tract infection (ED50 = 0.981 mg/kg).


1.Ozaki, M., Matsuda, M., Tomii, Y., et al.In vivo evaluation of NM441, a new thiazeto-quinoline derivativeAntimicrob. Agents Chemother.35(12)2496-2499(1991)

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