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  • Tenofovir alafenamide hemifumarate
Tenofovir alafenamide hemifumarate的可视化放大

Tenofovir alafenamide hemifumarate

Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for

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0-2640
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  • 库存: 现货
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  • 货号: ajce59760
  • CAS: 1392275-56-7
  • 别名: 替诺福韦艾拉酚胺富马酸盐,GS-7340 hemifumarate
  • 分子式: C21H29N6O5P.1/2 C4H4O4
  • 分子量: 534.5
  • 纯度: >98%
  • 溶解度: DMSO: 50 mg/mL (93.55 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.


[1] Amanda K Gibson, et al. Ann Pharmacother. 2016 Nov;50(11):942-952.

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