A natural antibiotic and anti-inflammatory alcohol
Pogostemon (patchouli) leaves and their extracted oils are used in perfumes and in traditional medicine to relieve sunstroke, stop vomiting, and increase appetite.1 Patchouli alcohol is a sesquiterpene alcohol found in patchouli oil. It has antibacterial, antifungal, and antiviral actions.1,2,3 Patchouli alcohol also suppresses inflammation induced by lipopolysaccharide in vivo.4 Topical application of patchouli alcohol accelerates recovery from ultraviolet irradiation-induced skin damage through antioxidant and anti-inflammatory effects.5
1.Zhang, R., Yan, P., Li, Y., et al.A pharmacokinetic study of patchouli alcohol after a single oral administration of patchouli alcohol or patchouli oil in ratsEur. J. Drug Metab. Pharmacokinet.41(4)441-448(2015) 2.Wu, H., Li, B., Wang, X., et al.Inhibitory effect and possible mechanism of action of patchouli alcohol against influenza A (H2N2) virusMolecules16(8)6489-6501(2011) 3.Yu, X.D., Xie, J.H., Wang, Y.H., et al.Selective antibacterial activity of patchouli alcohol against Helicobacter pylori based on inhibition of ureasePhytother. Res.29(1)67-72(2015) 4.Yu, J.L., Zhang, X.S., Xue, X., et al.Patchouli alcohol protects against lipopolysaccharide-induced acute lung injury in miceJ. Surg. Res.194(2)537-543(2015) 5.Feng, X.X., Yu, X.T., Li, W.J., et al.Effects of topical application of patchouli alcohol on the UV-induced skin photoaging in miceEur. J. Pharm. Sci.63113-123(2014)
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