Background:
(-)-Gallocatechin gallate is the polyphenol isolated from tea, with cancer-preventive activities.
The amount of (-)-Gallocatechin gallate does not differ in leaves of different stages, and the content is relatively low[1]. (?)-gallocatechin gallate in combination with active catechins ((?)-epigallocatechin gallate) has synergistic effects on the induction of apoptosis and inhibition of cell growth for PC-9 cells. (?)-gallocatechin gallate shows inhibitory effect on α-Glucosidase and DPPH, with IC50s of 30.2 μM and 12.2 μg/mL[2].
参考文献:
[1]. Zhang LQ, et al. Accumulation of catechins and expression of catechin synthetic genes in Camellia sinensis at different developmental stages. Bot Stud. 2016 Dec;57(1):31.
[2]. Zhou H, et al. C-geranylated flavanones from YingDe black tea and their antioxidant and α-glucosidase inhibition activities. Food Chem. 2017 Nov 15;235:227-233.
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