Parathyroid Hormone (1-34), bovine

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

可选规格

包装

价格

促销价

数量
1mg

￥1102.00

991.00

- +
5mg

￥2878.00

2590.00

- +
10mg

￥4720.00

4248.00

- +
25mg

￥7442.00

6697.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

Enhancer of blood calcium level

货号：ajcp4454
CAS：12583-68-5
分子式：C183H288N54O50S2
分子量：4108.71
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Parathyroid hormone (PTH) is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid, which is secreted by the chief cell of the parathyroid glands as a polypeptide containing 84 amino acids. It acts to increase the concentration of calcium (Ca²⁺) in the blood, whereas calcitonin (a hormone produced by the parafollicular cells (C cells) of the thyroid gland) acts to decrease calcium concentration.

PTH acts to increase the concentration of calcium in the blood by acting upon the parathyroid hormone 1 receptor (high levels in bone and kidney) and the parathyroid hormone 2 receptor (high levels in the central nervous system, pancreas, testis, and placenta).

PTH half-life is approximately 4 minutes. [1] Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged within the Golgi into secretory vesicles, the secreted into blood by exocytosis.

参考文献:
1. Bieglmayer C, Prager G, Niederle B (October 2002). "Kinetic analyses of parathyroid hormone clearance as measured by three rapid immunoassays during parathyroidectomy". Clin. Chem. 48 (10): 1731–8.