DSPE-PEG(2000)-NHS
A PEGylated derivative of DSPE
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包装价格促销价数量
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50mg￥1537.001230.00- +
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100mg￥2900.002320.00- +
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250mg￥6812.005450.00- +
- 货号: ajcf12466
- CAS:
- 别名:
- 分子式: (C2H4O)nC51H93N2O15P
- 分子量: 0
- 纯度: ＞98%
- 溶解度: DMF: insol,DMSO: insol,Ethanol: 5 mg/ml,PBS (pH 7.2): insol
- 储存: -20°C
- 库存: 现货
Background
DSPE-PEG(2000)-NHS is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE .1 It has been used in the generation of micelles and in combination with other lipids in the formation of liposomes. DSPE-PEG(2000)-NHS-containing liposomes localize to the liver and tumor after intravenous administration in mice. Liposomes containing DSPE-PEG(2000)-NHS conjugated to the breast cancer targeting H6 peptide and encapsulating the DNA topoisomerase inhibitor doxorubicin reduce tumor growth in an SK-BR-3 breast cancer mouse xenograft model.
1.Jia, X., Wang, W., Han, Q., et al.Micromixer based preparation of functionalized liposomes and targeting drug deliveryACS Med. Chem. Lett.7(4)429-434(2016)
