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Vapiprost hydrochloride 是一种血栓素 A2 受体拮抗剂。Vapiprost 抑制 U-46619、胶原蛋白或花生四烯酸 (AA) 刺激的聚集和 ATP 释放,IC50 小于 2.1×10-8 M。
Vapiprost hydrochloride is a thromboxane A2 receptor antagonist. Vapiprost inhibits the aggregation and ATP release stimulated with U-46619, collagen or arachidonic acid (AA) at an IC50 of less than 2.1×10-8 M[1].
[1]. Shuichi HORIE, et al. The Potent Inhibition of Vapiprost, a Novel Thromoboxane A2 Receptor Antagonist, on the Secondary Aggregation and ATP Release of Human Platelets.
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