TCO-PEG3-amine
TCO-PEG3-amine 是一种 PROTAC linker，属于 PEG 类。TCO-PEG3-amine 可用于合成一系列 PROTAC 分子。
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包装价格促销价数量
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25mg￥2312.001850.00- +
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100mg￥6587.005270.00- +
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250mg￥12787.0010230.00- +
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- 货号: ajcf16702
- CAS: 1800507-93-0
- 别名:
- 分子式: C17H32N2O5
- 分子量: 344.45
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -20°C
- 库存: 现货
Background
TCO-PEG3-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.
